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Our latest article highlights
IKOSA Prisma in Action: Assessing Angiogenesis Hallmarks Within the CAM Assay Model
We present to you a simple AI-driven method to analyze image data collected from the CAM assay model. Bear with us as we will explain to you how to effortlessly automate the entire image analysis process with the help of the IKOSA CAM Assay Application. Table of...
ROI, Annotation, Labels: Mastering Image Annotation in Pathology
Microscopy image annotation and pathology annotation, in particular, are tasks that require a lot of attention to detail. To be able to train Deep Learning Computer Vision Applications, which perform advanced tasks such as detection, segmentation, and classification...
Automated Data Adaptation for the Segmentation of Blood Vessels
This paper addresses domain shifts in image analysis for diagnostics, causing compatibility issues with AI models for segmentation. Two approaches...
Toxicological Analysis by Assessment of Vascularization and Cell Viability Using the Chicken’s Chorioallantoic Membrane (CAM Assay)
This paper presents a promising alternative in animal experimentation - the CAM assay using hen's eggs. The CAM provides a suitable environment for...
ROI, Annotation, Labels: Mastering Image Annotation in Pathology
Microscopy image annotation and pathology annotation, in particular, are tasks that require a lot of attention to detail. To be able to train Deep...
A New Way to Morphological Cell Profiling Using IKOSA’s Cell Painting Assay
The Cell Painting Assay provides researchers with a powerful tool for morphological cell profiling, enabling investigations into cellular behavior...
Automated Data Adaptation for the Segmentation of Blood Vessels
This paper addresses domain shifts in image analysis for diagnostics, causing compatibility issues with AI models for segmentation. Two approaches...
From Microscopic Patterns to Diagnostic Insights: Exploring the New Frontier of Blood and Inflammation with Prof. Johannes Schmid
Join us, as we embark on a captivating journey delving into the groundbreaking work and ongoing projects of Prof. Johannes Schmid from the Medical...
Learning From the JUMP CP Pilot Data: Insights for Platform Development
Together with Core Life Analytics, we have embarked on a collaborative project at the forefront of target and drug discovery. IKOSA and StratoMineR...
IKOSA Prisma in Action: Assessing Angiogenesis Hallmarks Within the CAM Assay Model
We present to you a simple AI-driven method to analyze image data collected from the CAM assay model. Bear with us as we will explain to you how to...
A Fast Approach for Fully-Automated Cell Painting Image Analysis and Feature Extraction from Raw Image Data
In this innovative collaboration with Core Life Analytics we aim to transform cell profiling and reproducible morphological profiling in the pursuit...
Toxicological Analysis by Assessment of Vascularization and Cell Viability Using the Chicken’s Chorioallantoic Membrane (CAM Assay)
This paper presents a promising alternative in animal experimentation - the CAM assay using hen's eggs. The CAM provides a suitable environment for...
Simplifying N:C Ratio Analysis in Cytology: An Easy Approach Using Image Analysis Software
In recent times histological assessment is considered the gold standard for assessing cell and tissue malignancy or the absence thereof. However, it...
The Key To Robust Translational Results In Preclinical Data Analysis
Mastering the art of preclinical data analysis is key to providing robust translational outcomes that are later used in clinical research. In this...
Drug Discovery Screening in Scalable Organotypic 3D Models
We joined forces with InSphero to advance the field of 3D organotypic modeling in drug discovery. Leveraging InSphero's expertise in developing...
Solving the Reproducibility Problem in Biomedical Research
The ongoing debate in the scientific community about whether studies in the life sciences are perfectly reproducible is often referred to as the...
Antagonistic Functions of Androgen Receptor and NF-κB in Prostate Cancer—Experimental and Computational Analyses
Prostate cancer is very frequent and is, in many countries, the third-leading cause of cancer-related death in men. While early diagnosis and...
The Chick Embryo Xenograft Model for Malignant Pleural Mesothelioma: A Cost and Time Efficient 3Rs Model for Drug Target Evaluation
Malignant pleural mesothelioma is a cancer of the lung lining, normally caused by asbestos, that develops decades after exposure. Chemotherapy, and...
Explainable AI für die KI-Validierung in der aseptischen Arzneimittelproduktion
Während künstliche Intelligenz in verschiedensten Unternehmen bereits erfolgreich eingesetzt wird, findet sie in hochregulierten Bereichen wie der...
The Latest Insights into Axon Regeneration Research
In this article, we throw light on the underlying mechanisms of axon regeneration. Axons play a central role in the recovery of neuronal functions...
IKOSA® CAM Assay Application to Quantify Blood Vessels on Chick Chorioallantoic Membrane (CAM)
Among in vivo angiogenesis assays, chick chorioallantoic membrane (CAM) assay has allowed meaningful progress in elucidating the mechanism of the...
A Novel Artificial Intelligence-Based Approach for Quantitative Assessment of Angiogenesis in the Ex Ovo CAM Model
Angiogenesis is a highly regulated process. It promotes tissue regeneration and contributes to tumor growth. Existing therapeutic concepts interfere...
The Principles of Colocalization Microscopy and Image Analysis
Colocalization microscopy and image analysis are some of the principal and most commonly used tools in modern biology to accurately localize...
Spatial Biology: Introducing Spatial Metrics to Bioimage Analysis
Spatial biology is a growing field in modern life science with a significant future potential. We dive deep into this exciting subject to keep you...
A 3D In Vivo Model for Studying Human Renal Cystic Tissue and Mouse Kidney Slices
(1) Background: Autosomal dominant polycystic kidney disease (ADPKD) is a frequent monogenic disorder that leads to progressive renal cyst growth...
ESWT Diminishes Axonal Regeneration following Repair of the Rat Median Nerve with Muscle-In-Vein Conduits but Not after Autologous Nerve Grafting
Investigations reporting positive effects of extracorporeal shockwave therapy (ESWT) on nerve regeneration are limited to the rat sciatic nerve...
Deep Learning-Based Image Analysis for the Quantification of Tumor-Induced Angiogenesis in the 3D In Vivo Tumor Model—Establishment and Addition to Laser Speckle Contrast Imaging (LSCI)
(1) Background: angiogenesis plays an important role in the growth and metastasis of tumors. We established the CAM assay application, an image...
Occurrence of Lymphangiogenesis in Peripheral Nerve Autografts Contrasts Schwann Cell-Induced Apoptosis of Lymphatic Endothelial Cells In Vitro
Peripheral nerve injuries pose a major clinical concern world-wide, and functional recovery after segmental peripheral nerve injury is often...
Pathologist Advice on Prostate Cancer Microscopy Analysis Techniques
Prostate microscopy is one of the areas where the use of pathology image analysis is on the rise and about to become standard diagnostic practice....
Unlocking the Full Potential of Multiplex IHC Analysis
Shifting from single marker analysis to more complex multiplex IHC analysis methods really makes a difference in immunohistochemistry studies. Yet,...
Master Bioimage Analysis Tasks with the IKOSA Knowledge Base
Since user education has always been a priority to us we have recently launched theIKOSA Knowledge Base - an extensive online repository...
REPAINT – The Artificial Intelligence Algorithm for Comprehensive Phenotyping of Conidial Fungi
In collaboration with the FungiG laboratory, we aim to advance the understanding of conidial fungi by developing a high-throughput phenotyping...
Nuclei Segmentation Using Deep Learning: Methodology Essentials
State-of-the-art nuclei segmentation techniques using deep learning technology solve many of the problems related to extracting...
Validation of AI-based Information Systems for Sensitive Use Cases: Using an XAI Approach in Pharmaceutical Engineering
Artificial Intelligence (AI) is adopted in many businesses. However, adoption lacks behind for use cases with regulatory or compliance requirements,...
Key Features You Should Look For In Pathology Image Analysis Software
Advanced pathology image analysis software solutions transform biomedical research practice. To provide you with a brief overview of the bioimage...
Advances in Alzheimer’s Research with Brain Organoids Technology
Find out how artificially cultivated human brain organoids and AI-backed image analysis software can facilitate the study of Alzheimer’s disease....
Microbiology Software in Action: a Best Practice Case Study
Find out how automated microbiology image analysis software revolutionizes fungal research. Learn about the latest applications of our AI-powered...
Prostate Tissue Histology with Computational Methods
Learn about the latest developments in prostate tissue histology, where the need for new automated image analysis methods is rapidly...
The Uses of CAM Assay Angiogenesis Analysis Software
As the chick chorioallantoic membrane (CAM) model raises in popularity in scientific literature, many researchers express interest in...
The Multifaceted Applications of Angiogenesis Quantification Software
In this article, we introduce five angiogenesis quantification software solutions that can help you leverage the potential of AI-driven image...
Evolutionary Compromises in Fungal Fitness: Hydrophobins can Hinder the Adverse Dispersal of Conidiospores and Challenge Their Survival
Fungal evolutionary biology is impeded by the scarcity of fossils, irregular life cycles, immortality, and frequent asexual reproduction. Simple and...
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